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BIOACTIVE

BIOACTIVE

Released: 2026-03-07
© 881375
BIOACTIVE - QR Code
81 Episodes
Audio
Listen on Apple Podcasts
81 Episodes
Audio
Listen on Apple Podcasts
Released: 2026-03-07
© 881375
Most Recent Episode
Beyond Caffeine: The Hidden Chemistry of Coffee with Dr. Steven Helschien (Dr. Coffee)

Beyond Caffeine: The Hidden Chemistry of Coffee with Dr. Steven Helschien (Dr. Coffee)

There are all sorts of misconceptions about coffee — that it dehydrates you, that it’s bad for your heart, or that caffeine is the only thing happening in the cup. Dr. Riley Kirk welcomes coffee scientist Dr. Steven Helschien, widely known as “D
Time: 1:09:33
There are all sorts of misconceptions about coffee — that it dehydrates you, that it’s bad for your heart, or that caffeine is the only thing happening in the cup.
Dr. Riley Kirk welcomes coffee scientist Dr. Steven Helschien, widely known as “Dr. Coffee,” for a fascinating conversation exploring the chemistry, health effects, and cultural significance of one of the world’s most widely consumed psychoactive plants: coffee. With a background in chemistry and extensive experience in coffee education and research, Dr. Helschien breaks down the complex science behind coffee in a way that is both practical and accessible.
They discuss coffee as a psychoactive plant medicine, examining not only caffeine but also the wide range of entourage compounds that influence its physiological and cognitive effects.
Dr. Helschien and Dr. Kirk explore coffee’s relationship with inflammation, liver health, and cardiovascular markers, unpacking what current research suggests about coffee consumption and long-term wellness. They also explore the importance of coffee quality, including concerns about mold contamination, sourcing practices, and what consumers should look for when choosing high-quality beans. The conversation touches on brewing techniques and the science of extraction, the chemistry behind decaffeination methods, and why caffeine affects the body the way it does.
The episode also expands into broader discussions about coffee as plant medicine, the cultural role of caffeine, and the fine line between daily ritual and dependence.
Dr. Helschien shares insights into mold-free coffee sourcing, considerations around caffeine and breastfeeding, and practical strategies like caffeine cycling to maintain sensitivity to its effects.
This is a conversation for anyone who loves coffee but wants to understand what’s really happening in the cup. Whether you're curious about caffeine’s effects, confused by common coffee myths, exploring brewing methods, or simply trying to get more out of your daily ritual, this episode offers science-backed insight in an accessible way. From the chemistry of flavor and roasting to the physiology of caffeine and the cultural habits surrounding coffee, Dr. Helschien helps demystify one of the world’s most widely consumed beverages.
Episode Chapters:
01:02 Meet Dr Coffee
02:08 Psychoactive Plant
03:04 Entourage Compounds
06:04 Inflammation And Liver
08:19 Quality And Mold
10:13 Brain Heart Plaque
23:43 Brewing And Decaf
35:43 Decaf Methods Explained
36:49 Why Caffeine Works
38:36 Coffee as Plant Medicine
39:39 Coffee Addiction and Culture
43:12 Mold Free Coffee Buying
45:49 Breastfeeding and Caffeine
47:20 Caffeine Cycling Hack
59:15 Community Q&A and Wrap Up
Get Free Coffee Science Resource from Dr. Helschien:
Doc@myhealthypatient.com
Connect with Dr. Helschien:
LinkedIn - Dr. Steven Helschien
Want Exclusive Content and Ad-Free Episodes?
Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one.
www.Patreon.com/Cannabichem
🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, pharmacology, and plant-based medicine!
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www.AppliedPharmacognosy.org
Keep Up with Dr. Riley Kirk
https://www.bioactivepodcast.com/
https://www.youtube.com/@cannabichem
https://instagram.com/cannabichem
https://www.appliedpharmacognosy.org/
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Episode ID: 1000753677521
GUID: 1cf18376-1982-11f1-8d74-bf3fffad1baa
Release Date: 07/03/2026, 01:39:00

Description

Dr. Riley Kirk is a cannabis research scientist and educator. She obtained her Ph.D. in pharmaceutical sciences, specializing in natural product chemistry, studying the traditional and contemporary uses of hundreds of medicinal plants. She is currently an assistant associate professor at the University of Rhode Island, has worked as an immunology scientist in the biotech industry, and works in the cannabis industry studying the chemical complexity of cannabis smoke.
Riley is also the co-founder of the cannabis research and education non-profit organization called the Network of Applied Pharmacognosy (NAP). Through NAP and on her podcast, Riley uses science as advocacy to research and communicate findings that highlight the unique power of natural products. The goal of Riley’s work is to unite people in the Cannabis industry, academia, and consumers to further the reach of Cannabis education and reduce harm.
Riley is passionate about making Cannabis science accessible through social media channels and alternative media which lead to Bioactive; an educational podcast which disseminates the chemistry and pharmacology of natural products. On this bi-weekly podcast, she covers current news and research surrounding cannabis, psychedelics, toxins, pharmaceuticals & other bioactive substances. Listen for special guests highlighting community stories.

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